Scientists from Malmö University in Sweden have proposed a new approach to treating migraines through the sublingual mucosa. The International Journal of Pharmaceuticals indicates that university researchers are conducting a study on alleviating migraine pain, believing that conventional migraine medications do not reach the bloodstream quickly enough to relieve the spasm occurring. Therefore, they decided to "shorten the route" by placing these pills under the tongue.
It is noted that most pain relief medications contain triptans, which interact with serotonin receptors, thereby suppressing pain signals in the brain centers. According to the researchers, "active substances are usually absorbed in the stomach or liver, and half of a triptan dose is consumed in the digestive system before it reaches the bloodstream. To achieve the desired effect, the maximum concentration of the substance in the blood must be reached within two hours, but this does not happen."
For this reason, the researchers opted to place the pills under the tongue so that the active ingredient would quickly enter the bloodstream through the mucosa of the oral cavity. The final results of these tests are expected to be announced in the spring of this year.
