The draw for the Round of 16 of the Europa League resulted in Barcelona facing Turkish team Galatasaray. The remaining matchups are as follows:
- Scottish Rangers vs. Serbian Red Star
- Portuguese Braga vs. French Monaco
- Portuguese Porto vs. French Lyon
- Italian Atalanta vs. German Bayer Leverkusen
- Spanish Sevilla vs. English West Ham United
- German Leipzig vs. Russian Spartak Moscow
- Spanish Real Betis vs. German Eintracht Frankfurt
The first leg matches will take place on March 10, while the return legs will be on March 17. The second leg matches will be held at the home grounds of the teams that topped their groups in the group stage of the competition. The quarterfinal matches are scheduled for April 7 and April 14.
