Researchers from the University of Virginia have discovered the potential to manipulate a gene to help stop the spread of small cell lung cancer, a type of tumor characterized by aggressive and uncontrolled rapid growth in the lungs. According to the journal "Science Advances," small cell lung cancer accounts for about 13% of malignant lung tumors.
The research findings indicate that if this tumor is detected early and before it spreads, this new treatment can control about 25% of cases. Professor Kwon Seok Park, who supervises the research, stated, "The current treatment for this type of tumor is weak, as only 7% of patients survive an average of 5 years after diagnosis."
He added, "The EP300 gene is extensively mutated, and it has been shown to play an important role in the treatment of other tumors, including leukemia and triple-negative breast cancer. Our research has demonstrated that it is effective in preventing the spread of small cell lung cancer." Scientists hope that the discovery of the role of the EP300 gene will lead to a new approach for treating a range of cancers, particularly lung cancer.