A large-scale study of the human genome has found a causal relationship between migraine and blood sugar levels, linking these traits to elevated fasting blood sugar and increased glucose levels two hours after a meal. The study was conducted by Dr. Dali Nieholt and researcher Rafiq Islam from the University of Queensland, and the results were published in the journal "Human Genetics," which specializes in genetic studies. Dr. Nieholt stated, "About 15% of the world's population suffers from migraines, and until 1935, it was described as (blood sugar headache)."
The researchers analyzed hundreds of thousands of human genomes from migraine patients, individuals with recurring headaches, and those without. Nieholt mentioned, "By mapping the genetic associations and shared genes, we deduced a causal connection, enhancing our understanding of the relationship between migraine and glycemic traits," referring to blood sugar characteristics. Researcher Rafiq Islam noted, "Among the nine glycemic traits we studied, we found a significant genetic association between fasting insulin (morning blood insulin level) and glycosylated hemoglobin with both migraine and headaches." The results indicated a genetic connection between elevated glucose levels two hours after eating and migraine. Islam added, "The findings provide pathways for developing new therapeutic strategies to manage glycemic traits in migraine and headache patients, particularly increasing fasting insulin levels to protect against headaches."
